4w92: Difference between revisions

<StructureSection load='4w92' size='340' side='right'caption='[[4w92]], [[Resolution|resolution]] 3.21&Aring;' scene=''>

<table><tr><td colspan='2'>[[4w92]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4W92 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2BA:(2R,3R,3AS,5R,7AR,9R,10R,10AS,12R,14AR)-2,9-BIS(6-AMINO-9H-PURIN-9-YL)OCTAHYDRO-2H,7H-DIFURO[3,2-D 3,2-J][1,3,7,9,2,8]TETRAOXADIPHOSPHACYCLODODECINE-3,5,10,12-TETROL+5,12-DIOXIDE'>2BA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4w92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w92 OCA], [https://pdbe.org/4w92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4w92 RCSB], [https://www.ebi.ac.uk/pdbsum/4w92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4w92 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref>  

*[[Riboswitch 3D structures|Riboswitch 3D structures]]

[[Category: Bacillus subtilis]]

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Ferre-D'Amare AR]]

[[Category: Jones CP]]