4ncj: Difference between revisions

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==Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation with ADP Beryllium Flouride==
==Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation with ADP Beryllium Flouride==
<StructureSection load='4ncj' size='340' side='right' caption='[[4ncj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4ncj' size='340' side='right'caption='[[4ncj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ncj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NCJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NCJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ncj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NCJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NCJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4nch|4nch]], [[4nci|4nci]], [[4nck|4nck]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ncj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ncj OCA], [https://pdbe.org/4ncj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ncj RCSB], [https://www.ebi.ac.uk/pdbsum/4ncj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ncj ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF1167, rad50 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ncj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ncj OCA], [http://pdbe.org/4ncj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ncj RCSB], [http://www.ebi.ac.uk/pdbsum/4ncj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ncj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RAD50_PYRFU RAD50_PYRFU]] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449]  
[https://www.uniprot.org/uniprot/RAD50_PYRFU RAD50_PYRFU] Involved in DNA double-strand break repair (DSBR). The Rad50/Mre11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific 3'-5' exonuclease activity. Rad50 provides an ATP-dependent control of Mre11 by unwinding and/or repositioning DNA ends into the Mre11 active site.[HAMAP-Rule:MF_00449]
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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<div class="pdbe-citations 4ncj" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4ncj" style="background-color:#fffaf0;"></div>
==See Also==
*[[ATPase 3D structures|ATPase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pyrfu]]
[[Category: Large Structures]]
[[Category: Arvai, A S]]
[[Category: Pyrococcus furiosus DSM 3638]]
[[Category: Classen, S]]
[[Category: Arvai AS]]
[[Category: Williams, G J]]
[[Category: Classen S]]
[[Category: Williams, R S]]
[[Category: Williams GJ]]
[[Category: Adenosine triphosphatase]]
[[Category: Williams RS]]
[[Category: Dna binding protein]]
[[Category: Dna repair]]
[[Category: Fungal protein]]

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