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==Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the | ==Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.== | ||
<StructureSection load='4owp' size='340' side='right' caption='[[4owp]], [[Resolution|resolution]] 2.35Å' scene=''> | <StructureSection load='4owp' size='340' side='right'caption='[[4owp]], [[Resolution|resolution]] 2.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4owp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OWP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OWP FirstGlance]. <br> | <table><tr><td colspan='2'>[[4owp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OWP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OWP FirstGlance]. <br> | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/RPN8_YEAST RPN8_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:9584156</ref> [[http://www.uniprot.org/uniprot/RPN11_YEAST RPN11_YEAST]] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:21075847</ref> | [[http://www.uniprot.org/uniprot/RPN8_YEAST RPN8_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:9584156</ref> [[http://www.uniprot.org/uniprot/RPN11_YEAST RPN11_YEAST]] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:21075847</ref> | ||
==See Also== | |||
*[[Proteasome 3D structures|Proteasome 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Baker's yeast]] | [[Category: Baker's yeast]] | ||
[[Category: Large Structures]] | |||
[[Category: Dvir, H]] | [[Category: Dvir, H]] | ||
[[Category: Glickman, M H]] | [[Category: Glickman, M H]] | ||
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[[Category: Metalloprotease]] | [[Category: Metalloprotease]] | ||
[[Category: Mpn domain]] | [[Category: Mpn domain]] | ||
[[Category: | [[Category: Proteasome]] | ||
[[Category: Ubiquitin]] | [[Category: Ubiquitin]] | ||
[[Category: Zinc]] | [[Category: Zinc]] | ||
Revision as of 11:21, 18 December 2019
Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.
Structural highlights
Function[RPN8_YEAST] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.[1] [RPN11_YEAST] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.[2] See AlsoReferences
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