3t6c: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older editNewer edit →
No edit summary
No edit summary
Line 1: Line 1:


==Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg==
==Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg==
<StructureSection load='3t6c' size='340' side='right' caption='[[3t6c]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='3t6c' size='340' side='right'caption='[[3t6c]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3t6c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Panam Panam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T6C FirstGlance]. <br>
<table><tr><td colspan='2'>[[3t6c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Panam Panam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T6C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T6C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GCO:GLUCONIC+ACID'>GCO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GCO:GLUCONIC+ACID'>GCO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rspA, PANA_0592 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=706191 PANAM])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rspA, PANA_0592 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=706191 PANAM])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t6c OCA], [http://pdbe.org/3t6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t6c RCSB], [http://www.ebi.ac.uk/pdbsum/3t6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t6c ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t6c OCA], [https://pdbe.org/3t6c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t6c RCSB], [https://www.ebi.ac.uk/pdbsum/3t6c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t6c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DGD_PANAM DGD_PANAM]] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>   
[[https://www.uniprot.org/uniprot/DGD_PANAM DGD_PANAM]] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>   
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Panam]]
[[Category: Panam]]
[[Category: Almo, S C]]
[[Category: Almo, S C]]

Revision as of 19:45, 6 July 2022

Crystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mgCrystal structure of an enolase from pantoea ananatis (efi target efi-501676) with bound d-gluconate and mg

Structural highlights

3t6c is a 2 chain structure with sequence from Panam. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , ,
Gene:rspA, PANA_0592 (PANAM)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[DGD_PANAM] Has low D-gluconate dehydratase activity (in vitro), suggesting that it has no significant role in D-gluconate degradation in vivo. Has no detectable activity with a panel of 70 other acid sugars (in vitro).[1]

References

  1. ↑ Wichelecki DJ, Balthazor BM, Chau AC, Vetting MW, Fedorov AA, Fedorov EV, Lukk T, Patskovsky YV, Stead MB, Hillerich BS, Seidel RD, Almo SC, Gerlt JA. Discovery of function in the enolase superfamily: D-mannonate and d-gluconate dehydratases in the D-mannonate dehydratase subgroup. Biochemistry. 2014 Apr 29;53(16):2722-31. doi: 10.1021/bi500264p. Epub 2014 Apr, 15. PMID:24697546 doi:http://dx.doi.org/10.1021/bi500264p

3t6c, resolution 1.60Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=3t6c&oldid=3587888"