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==Crystal Structure of BlaC-E166A covalently bound with Carbenicillin==
==Crystal Structure of BlaC-E166A covalently bound with Carbenicillin==
<StructureSection load='3n8r' size='340' side='right' caption='[[3n8r]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
<StructureSection load='3n8r' size='340' side='right'caption='[[3n8r]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3n8r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N8R FirstGlance]. <br>
<table><tr><td colspan='2'>[[3n8r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N8R FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CB9:(2R,4S)-2-[(1R)-1-{[(2S)-2-CARBOXY-2-PHENYLACETYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>CB9</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CB9:(2R,4S)-2-[(1R)-1-{[(2S)-2-CARBOXY-2-PHENYLACETYL]AMINO}-2-OXOETHYL]-5,5-DIMETHYL-1,3-THIAZOLIDINE-4-CARBOXYLIC+ACID'>CB9</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaA, blaC, MT2128, MTCY49.07c, Rv2068c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n8r OCA], [http://pdbe.org/3n8r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3n8r RCSB], [http://www.ebi.ac.uk/pdbsum/3n8r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3n8r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n8r OCA], [https://pdbe.org/3n8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n8r RCSB], [https://www.ebi.ac.uk/pdbsum/3n8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n8r ProSAT]</span></td></tr>
</table>
</table>
==See Also==
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Beta-lactamase]]
[[Category: Large Structures]]
[[Category: Blanchard, J S]]
[[Category: Blanchard, J S]]
[[Category: Tremblay, L W]]
[[Category: Tremblay, L W]]

Revision as of 09:57, 12 May 2022

Crystal Structure of BlaC-E166A covalently bound with CarbenicillinCrystal Structure of BlaC-E166A covalently bound with Carbenicillin

Structural highlights

3n8r is a 1 chain structure with sequence from "bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:blaA, blaC, MT2128, MTCY49.07c, Rv2068c ("Bacillus tuberculosis" (Zopf 1883) Klein 1884)
Activity:Beta-lactamase, with EC number 3.5.2.6
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

See Also

3n8r, resolution 1.41Å

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