3m6e: Difference between revisions

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==F80A mutant of the Urea Transporter from Desulfovibrio Vulgaris==
==F80A mutant of the Urea Transporter from Desulfovibrio Vulgaris==
<StructureSection load='3m6e' size='340' side='right' caption='[[3m6e]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='3m6e' size='340' side='right'caption='[[3m6e]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3m6e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Desvh Desvh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M6E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M6E FirstGlance]. <br>
<table><tr><td colspan='2'>[[3m6e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Desvh Desvh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M6E FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AU:GOLD+ION'>AU</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AU:GOLD+ION'>AU</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DVU_1160 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=882 DESVH])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DVU_1160 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=882 DESVH])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m6e OCA], [http://pdbe.org/3m6e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3m6e RCSB], [http://www.ebi.ac.uk/pdbsum/3m6e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3m6e ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m6e OCA], [https://pdbe.org/3m6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m6e RCSB], [https://www.ebi.ac.uk/pdbsum/3m6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m6e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UT_DESVH UT_DESVH]] Urea channel that facilitates transmembrane urea transport down a concentration gradient.<ref>PMID:19865084</ref>   
[[https://www.uniprot.org/uniprot/UT_DESVH UT_DESVH]] Urea channel that facilitates transmembrane urea transport down a concentration gradient.<ref>PMID:19865084</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m6/3m6e_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m6/3m6e_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m6e ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m6e ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[Urea transporter|Urea transporter]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Desvh]]
[[Category: Desvh]]
[[Category: Large Structures]]
[[Category: Levin, E J]]
[[Category: Levin, E J]]
[[Category: NYCOMPS, New York Consortium on Membrane Protein Structure]]
[[Category: NYCOMPS, New York Consortium on Membrane Protein Structure]]

Revision as of 08:37, 6 October 2021

F80A mutant of the Urea Transporter from Desulfovibrio VulgarisF80A mutant of the Urea Transporter from Desulfovibrio Vulgaris

Structural highlights

3m6e is a 1 chain structure with sequence from Desvh. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:DVU_1160 (DESVH)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[UT_DESVH] Urea channel that facilitates transmembrane urea transport down a concentration gradient.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Levin EJ, Quick M, Zhou M. Crystal structure of a bacterial homologue of the kidney urea transporter. Nature. 2009 Dec 10;462(7274):757-61. Epub . PMID:19865084 doi:10.1038/nature08558

3m6e, resolution 2.65Å

Drag the structure with the mouse to rotate

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OCA