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==Structure of N-glycosylated porcine surfactant protein-D complexed with glycerol== | |||
<StructureSection load='6bbd' size='340' side='right' caption='[[6bbd]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6bbd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6BBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6BBD FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4dn8|4dn8]]</td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6bbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6bbd OCA], [http://pdbe.org/6bbd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6bbd RCSB], [http://www.ebi.ac.uk/pdbsum/6bbd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6bbd ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Haagsman, H | == Function == | ||
[[Category: | [[http://www.uniprot.org/uniprot/SFTPD_PIG SFTPD_PIG]] Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties (By similarity). | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Cafarella, T R]] | |||
[[Category: Die, I van]] | |||
[[Category: Eijk, M van]] | |||
[[Category: Haagsman, H P]] | |||
[[Category: Hartshorn, K L]] | |||
[[Category: Hessing, M]] | |||
[[Category: Khatri, K]] | [[Category: Khatri, K]] | ||
[[Category: Leymarie, N]] | [[Category: Leymarie, N]] | ||
[[Category: | [[Category: Rynkiewicz, M J]] | ||
[[Category: | [[Category: Seaton, B A]] | ||
[[Category: | [[Category: White, M R]] | ||
[[Category: Zaia, J]] | [[Category: Zaia, J]] | ||
[[Category: | [[Category: C-type lectin]] | ||
[[Category: Innate immunity]] | |||
[[Category: N-linked glycan]] | |||
[[Category: Surfactant]] | |||
[[Category: Surfactant protein]] | |||
Revision as of 10:19, 23 May 2018
Structure of N-glycosylated porcine surfactant protein-D complexed with glycerolStructure of N-glycosylated porcine surfactant protein-D complexed with glycerol
Structural highlights
Function[SFTPD_PIG] Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties (By similarity). |
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