217d: Difference between revisions

Revision as of 18:19, 3 May 2008

CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN

OverviewOverview

Two DNA-RNA chimers, complexed with DNA minor groove binding drugs, have been observed to adopt the B-form conformation for the first time. Thus, the RNA duplex may assume the B-DNA conformation when interacting with drugs, peptides or proteins.

About this StructureAbout this Structure

Full crystallographic information is available from OCA.

ReferenceReference

Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:7552741 Page seeded by OCA on Sat May 3 18:19:12 2008

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OCA

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 [[Image:217d.gif|left|200px]]
- {{Structure
+<!--
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 '''CRYSTAL STRUCTURES OF THE B-FORM DNA-RNA CHIMER (5'-D(*IP*)-R(*CP*)-D(*IP*)-R(*CP*)-D(*IP*CP*IP*C)-3') COMPLEXED WITH DISTAMYCIN'''
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 ==About this Structure==
-D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=217D OCA].
+Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=217D OCA].
 ==Reference==
 Crystal structures of B-form DNA-RNA chimers complexed with distamycin., Chen X, Ramakrishnan B, Sundaralingam M, Nat Struct Biol. 1995 Sep;2(9):733-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7552741 7552741]
-[[Category: Protein complex]]
 [[Category: Chen, X.]]
 [[Category: Ramakrishnan, B.]]
 [[Category: Sundaralingam, M.]]
-[[Category: b-dna/rna]]
+[[Category: B-dna/rna]]
-[[Category: complexed with drug]]
+[[Category: Complexed with drug]]
-[[Category: double helix]]
+[[Category: Double helix]]
-[[Category: modified]]
+[[Category: Modified]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 18:19:12 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:44:20 2008''