210d: Difference between revisions

Revision as of 18:18, 3 May 2008

CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A)CG] AND ITS PLATINATED DERIVATIVE

OverviewOverview

The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous with other DNA hexanucleotides. Despite completely different crystal packing, the essential characteristics of the Z-DNA conformation are maintained. The structure was determined by single isomorphous replacement using a triammine platinum fragment. Thus, this study also demonstrates, for the first time, the feasibility of the use of this reagent for the direct phasing of DNA crystal structures.

About this StructureAbout this Structure

Full crystallographic information is available from OCA.

ReferenceReference

Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:7492550 Page seeded by OCA on Sat May 3 18:18:25 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 [[Image:210d.gif|left|200px]]
- {{Structure
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 '''CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A)CG] AND ITS PLATINATED DERIVATIVE'''
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 ==About this Structure==
-D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=210D OCA].
+Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=210D OCA].
 ==Reference==
 Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7492550 7492550]
-[[Category: Protein complex]]
 [[Category: Arvantis, G M.]]
 [[Category: Berman, H M.]]
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 [[Category: Lessinger, L.]]
 [[Category: Parkinson, G N.]]
-[[Category: double helix]]
+[[Category: Double helix]]
-[[Category: modified]]
+[[Category: Modified]]
-[[Category: z-dna]]
+[[Category: Z-dna]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 18:18:25 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:44:11 2008''