User:Jaime Prilusky/Test/references: Difference between revisions

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== '''SsoPox''' ==

Sso Pox is a protein of 314 aa deriving from the hyperthermophilic archaeon ''Sulfolobus solfataricus'' and it is the first protein with phosphotriesterase activities to be identified in Archaea. It has an exceptional thermal stability with denaturation half-life of 4h and 90 min at 95 °C and 100 °C <ref name="Merone"/><ref name='Porzio'/>.

Its activity depends on the presence of metal ions, with cobalt significantly enhancing catalysis. SsoPox have been reported to catalyse the hydrolysis of different N-acyl homoserine lactones AHLs; suggesting a physiological role as a quorum quencher lactonase. Infact the AHLs are natural molecules involved in the cell–cell communication process known as quorum sensing (QS) and any bacterial species may produce different AHLs, which vary in the length and substitution of the acyl chain. The anti-QS mechanisms of the enzyme works by the hydrolysis of the lactone bond of these AHLs. <ref name='Afriat'/>

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 == '''SsoPox''' ==
 Sso Pox is a protein of 314 aa deriving from the hyperthermophilic archaeon ''Sulfolobus solfataricus'' and it is the first protein with phosphotriesterase activities to be identified in Archaea. It has an exceptional thermal stability with denaturation half-life of 4h and 90 min at 95 °C and 100 °C  <ref name="Merone"/><ref name='Porzio'/>.
 Its activity depends on the presence of metal ions, with cobalt significantly enhancing catalysis. SsoPox have been reported to catalyse the hydrolysis of different N-acyl homoserine lactones AHLs;  suggesting a physiological role as a quorum quencher lactonase. Infact the AHLs are natural molecules involved in the cell–cell communication process known as quorum sensing (QS) and any bacterial species may produce different AHLs, which vary in the length and substitution of the acyl chain. The anti-QS mechanisms of the enzyme works  by the hydrolysis of the lactone bond of these AHLs. <ref name='Afriat'/>