3d9y: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal Structure of Profilin from Schizosaccharomyces pombe== | ==Crystal Structure of Profilin from Schizosaccharomyces pombe== | ||
<StructureSection load='3d9y' size='340' side='right' caption='[[3d9y]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='3d9y' size='340' side='right'caption='[[3d9y]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3d9y]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3d9y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3D9Y FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dav|3dav]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3dav|3dav]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cdc3, SPAC4A8.15c ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cdc3, SPAC4A8.15c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 CBS 356])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3d9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3d9y OCA], [https://pdbe.org/3d9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3d9y RCSB], [https://www.ebi.ac.uk/pdbsum/3d9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3d9y ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/PROF_SCHPO PROF_SCHPO]] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. In S.pombe, it is essential for cytokinesis. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 20: | ||
</div> | </div> | ||
<div class="pdbe-citations 3d9y" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3d9y" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Profilin 3D Structures|Profilin 3D Structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 25: | Line 28: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cbs 356]] | [[Category: Cbs 356]] | ||
[[Category: Large Structures]] | |||
[[Category: Ezezika, O C]] | [[Category: Ezezika, O C]] | ||
[[Category: Nolen, B J]] | [[Category: Nolen, B J]] | ||