Succinyl-CoA synthetase: Difference between revisions
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<StructureSection load='1cqj' size='350' side='right' scene='' caption='E. coli succinyl-CoA synthetase α subunit (grey, yellow) and β subunit (green, magenta) complex with CoA and phosphate (PDB code [[1cqj]])'> | <StructureSection load='1cqj' size='350' side='right' scene='' caption='E. coli succinyl-CoA synthetase α subunit (grey, yellow) and β subunit (green, magenta) complex with CoA and phosphate (PDB code [[1cqj]])'> | ||
'''Succinyl-CoA synthetase''' catalyzes the reversible reaction of succinyl-CoA + NDP + Pi <-> succinate + CoA + NTP (where N is either adenosine or guanosine. It can be found in Escherichia coli and is the fifth step in the [[Citric Acid Cycle|citric acid cycle]]. Due to its involvement in the citric acid cycle it is very important in all living cells that use oxygen as a part of cellular respiration. This entire process (Citric acid cycle) is necessary in producing one GTP or ATP, three NADHs, and two carbon dioxides. See also:<br /> | '''Succinyl-CoA synthetase''' or '''succinate-CoA ligase''' catalyzes the reversible reaction of succinyl-CoA + NDP + Pi <-> succinate + CoA + NTP (where N is either adenosine or guanosine. It can be found in Escherichia coli and is the fifth step in the [[Citric Acid Cycle|citric acid cycle]]. Due to its involvement in the citric acid cycle it is very important in all living cells that use oxygen as a part of cellular respiration. This entire process (Citric acid cycle) is necessary in producing one GTP or ATP, three NADHs, and two carbon dioxides. See also:<br /> | ||
*[[Krebs cycle carbons]] | *[[Krebs cycle carbons]] | ||
*[[Krebs cycle importance]] | *[[Krebs cycle importance]] | ||
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**[[1eud]] – pSCS α+β (mutant) subunit - pig<br /> | **[[1eud]] – pSCS α+β (mutant) subunit - pig<br /> | ||
**[[2fp4]] - pSCS α+β subunit + Mg + GTP<br /> | **[[2fp4]] - pSCS α+β subunit + Mg + GTP<br /> | ||
**[[2fpi]], [[2fpp]] - pSCS α+β subunit | **[[2fpi]], [[2fpp]] - pSCS α+β subunit<br /> | ||
**[[6g4q]] - hSCS α+β subunits - human<br /> | |||
*Dephosphorylated succinyl-CoA synthetase | *Dephosphorylated succinyl-CoA synthetase | ||
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**[[2yv1]] - SCS α subunit – ''Methanocaldococcus jannaschii''<br /> | **[[2yv1]] - SCS α subunit – ''Methanocaldococcus jannaschii''<br /> | ||
**[[2yv2]] - SCS α subunit – ''Aeropyrum pernix''<br /> | **[[2yv2]] - SCS α subunit – ''Aeropyrum pernix''<br /> | ||
**[[3ufx]] - SCS α+β subunits + Mn + GDP – ''Thermus aquaticus'' | **[[3ufx]] - SCS α+β subunits + Mn + GDP – ''Thermus aquaticus''<br /> | ||
**[[6mel]] - SCS α+β subunits + citrate – ''Campylobacter jejuni''<br /> | |||
}} | }} | ||
==Additional Resources== | ==Additional Resources== | ||