5qcc: Difference between revisions

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-'''Unreleased structure'''
-The entry 5qcc is ON HOLD
+==Crystal structure of human Cathepsin-S with bound ligand==
+<StructureSection load='5qcc' size='340' side='right' caption='[[5qcc]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-Authors: Yang, H., Shao, C., Burley, S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5qcc]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QCC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QCC FirstGlance]. <br>
-Description: Ligand binding to Cathepsin S
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGY:tert-butyl+4-(2-{3-(4-chloro-3-iodophenyl)-1-[3-(morpholin-4-yl)propyl]-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}-2-oxoethyl)piperidine-1-carboxylate'>BGY</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>
-[[Category: Burley, S]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qcc OCA], [http://pdbe.org/5qcc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qcc RCSB], [http://www.ebi.ac.uk/pdbsum/5qcc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qcc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
+__TOC__
+</StructureSection>
+[[Category: Cathepsin S]]
+[[Category: Ameriks, M K]]
+[[Category: Bembenek, S D]]
+[[Category: Burley, S K]]
+[[Category: Mirzadegan, T]]
+[[Category: Shao, C]]
 [[Category: Yang, H]]
-[[Category: Shao, C]]
+[[Category: Cathepsin s]]
+[[Category: D3r]]
+[[Category: Hydrolase]]
+[[Category: Ligand docking]]