5ol9: Difference between revisions

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'''Unreleased structure'''


The entry 5ol9 is ON HOLD
==Structure of human mitochondrial transcription elongation factor (TEFM) N-terminal domain==
 
<StructureSection load='5ol9' size='340' side='right' caption='[[5ol9]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5ol9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OL9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OL9 FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ol8|5ol8]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ol9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ol9 OCA], [http://pdbe.org/5ol9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ol9 RCSB], [http://www.ebi.ac.uk/pdbsum/5ol9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ol9 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TEFM_HUMAN TEFM_HUMAN]] Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery.<ref>PMID:21278163</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Agaronyan, K]]
[[Category: Anikin, M]]
[[Category: Chernev, A]]
[[Category: Cramer, P]]
[[Category: Graber, J J]]
[[Category: Hillen, H S]]
[[Category: Morozov, Y]]
[[Category: Parshin, A V]]
[[Category: Schwinghammer, K]]
[[Category: Temiakov, D]]
[[Category: Urlaub, H]]
[[Category: Elongation factor]]
[[Category: Mitochondria]]
[[Category: Resolvase]]
[[Category: Rna polymerase]]
[[Category: Transcription]]

Revision as of 10:12, 18 October 2017

Structure of human mitochondrial transcription elongation factor (TEFM) N-terminal domainStructure of human mitochondrial transcription elongation factor (TEFM) N-terminal domain

Structural highlights

5ol9 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[TEFM_HUMAN] Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery.[1]

References

  1. ↑ Minczuk M, He J, Duch AM, Ettema TJ, Chlebowski A, Dzionek K, Nijtmans LG, Huynen MA, Holt IJ. TEFM (c17orf42) is necessary for transcription of human mtDNA. Nucleic Acids Res. 2011 May;39(10):4284-99. doi: 10.1093/nar/gkq1224. Epub 2011, Jan 28. PMID:21278163 doi:10.1093/nar/gkq1224

5ol9, resolution 1.30Å

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