5vqy: Difference between revisions
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==Crystal Structure of HIV-1 Reverse Transcriptase (K103N, Y181C) Variant in Complex with N-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-N-methylacrylamide (JLJ684), a Non-nucleoside Inhibitor== | ==Crystal Structure of HIV-1 Reverse Transcriptase (K103N, Y181C) Variant in Complex with N-(6-cyano-3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-4-methylnaphthalen-1-yl)-N-methylacrylamide (JLJ684), a Non-nucleoside Inhibitor== | ||
<StructureSection load='5vqy' size='340' side='right' caption='[[5vqy]], [[Resolution|resolution]] 2.35Å' scene=''> | <StructureSection load='5vqy' size='340' side='right'caption='[[5vqy]], [[Resolution|resolution]] 2.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5vqy]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VQY FirstGlance]. <br> | <table><tr><td colspan='2'>[[5vqy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5VQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5VQY FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9J1:N-(6-cyano-3-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-4-methylnaphthalen-1-yl)-N-methylpropanamide'>9J1</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9J1:N-(6-cyano-3-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-4-methylnaphthalen-1-yl)-N-methylpropanamide'>9J1</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ter|5ter]], [[5vqv|5vqv]], [[5vqx|5vqx]], [[5vqz|5vqz]], [[5vqq|5vqq]], [[5vqr|5vqr]], [[5vqs|5vqs]], [[5vqt|5vqt]], [[5vqu|5vqu]], [[5vqw|5vqw]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ter|5ter]], [[5vqv|5vqv]], [[5vqx|5vqx]], [[5vqz|5vqz]], [[5vqq|5vqq]], [[5vqr|5vqr]], [[5vqs|5vqs]], [[5vqt|5vqt]], [[5vqu|5vqu]], [[5vqw|5vqw]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11678 HIV-1])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vqy OCA], [http://pdbe.org/5vqy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vqy RCSB], [http://www.ebi.ac.uk/pdbsum/5vqy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vqy ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5vqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5vqy OCA], [http://pdbe.org/5vqy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5vqy RCSB], [http://www.ebi.ac.uk/pdbsum/5vqy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5vqy ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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</div> | </div> | ||
<div class="pdbe-citations 5vqy" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5vqy" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Reverse transcriptase|Reverse transcriptase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Hiv-1]] | |||
[[Category: Large Structures]] | |||
[[Category: Anderson, K S]] | [[Category: Anderson, K S]] | ||
[[Category: Chan, A H]] | [[Category: Chan, A H]] |