Formate dehydrogenase: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Revision as of 11:49, 22 May 2017 view source Michal Harel (talk \| contribs) 31,761 edits No edit summary ← Older edit		Revision as of 22:14, 19 October 2017 view source Michal Harel (talk \| contribs) 31,761 edits No edit summary Newer edit →
Line 1:		Line 1:
	<StructureSection load='2nad' size='~~450~~' side='right' scene='49/491980/Cv/1' caption='NAD-dependent formate dehydrogenase dimer complex with cofactor NAD and sulfate, [[2nad]]'>		<StructureSection load='2nad' size='350' side='right' scene='49/491980/Cv/1' caption='NAD-dependent formate dehydrogenase dimer complex with cofactor NAD and sulfate, [[2nad]]'>

	'''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either [[NAD]]+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe<sub>4</sub>S<sub>4</sub> center and then to cytochrome. The '''Mo-dependent FDH-H''' from ''E. coli'' contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe<sub>4</sub>S<sub>4</sub><ref>PMID:2094290</ref>.		'''Formate dehydrogenase''' (FDH) catalyzes the reversible two-electron oxidation of formate to bicarbonate. The product electron is donated to either [[NAD]]+ in NAD-dependent FDH or to Mo-dependent FDH where the electron is donated to a Fe<sub>4</sub>S<sub>4</sub> center and then to cytochrome. The '''Mo-dependent FDH-H''' from ''E. coli'' contains SelCys, Mo, molybdopterin guanosine dinucleotide (MGD) cofactor and Fe<sub>4</sub>S<sub>4</sub><ref>PMID:2094290</ref>.