1uzc: Difference between revisions

Revision as of 11:53, 3 May 2008

THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11

OverviewOverview

The FF domain is a 60 amino acid residue phosphopeptide-binding module found in a variety of eukaryotic proteins including the transcription elongation factor CA150, the splicing factor Prp40 and p190RHOGAP. We have determined the structure of an FF domain from HYPA/FBP11. The domain is composed of three alpha helices arranged in an orthogonal bundle with a 3(10) helix in the loop between the second and third alpha helices. The structure differs from those of other phosphopeptide-binding domains and represents a novel phosphopeptide-binding fold.

About this StructureAbout this Structure

1UZC is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1h40. Full crystallographic information is available from OCA.

ReferenceReference

The structure of an FF domain from human HYPA/FBP11., Allen M, Friedler A, Schon O, Bycroft M, J Mol Biol. 2002 Oct 25;323(3):411-6. PMID:12381297 Page seeded by OCA on Sat May 3 11:53:52 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 [[Image:1uzc.gif|left|200px]]
- {{Structure
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 '''THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11'''
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 ==About this Structure==
-UZC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1H40. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZC OCA].
+UZC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1h40 1h40]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZC OCA].
 ==Reference==
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 [[Category: Jemth, P.]]
 [[Category: Schon, O.]]
-[[Category: nmr structure]]
+[[Category: Nmr structure]]
-[[Category: nuclear protein]]
+[[Category: Nuclear protein]]
-[[Category: phosphopeptide recognition]]
+[[Category: Phosphopeptide recognition]]
-[[Category: rna polymerase ii carboxyl-terminal domain]]
+[[Category: Rna polymerase ii carboxyl-terminal domain]]
-[[Category: transcription]]
+[[Category: Transcription]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 11:53:52 2008''
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:17:27 2008''