5gv5: Difference between revisions

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'''Unreleased structure'''


The entry 5gv5 is ON HOLD  until Paper Publication
==Crystal structure of Candida antarctica Lipase B with active Ser105 modified with a phosphonate inhibitor==
 
<StructureSection load='5gv5' size='340' side='right' caption='[[5gv5]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
Authors: Park, S.Y., Lee, H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5gv5]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GV5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GV5 FirstGlance]. <br>
Description: Crystal structure of Candida antarctica Lipase B with active Ser105 modified with a phosphonate inhibitor
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSW:[(1S)-2-(methoxycarbonylamino)-1-phenyl-ethoxy]-propyl-phosphinic+acid'>MSW</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gv5 OCA], [http://pdbe.org/5gv5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gv5 RCSB], [http://www.ebi.ac.uk/pdbsum/5gv5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gv5 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/LIPB_PSEA2 LIPB_PSEA2]] Hydrolysis of triglycerides. Is very stereospecific both in hydrolysis and in organic synthesis and has a potentially important application in glucolipid synthesis.
__TOC__
</StructureSection>
[[Category: Triacylglycerol lipase]]
[[Category: Lee, H]]
[[Category: Lee, H]]
[[Category: Park, S.Y]]
[[Category: Park, S Y]]
[[Category: Cal-b]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Inhibitor]]
[[Category: Lipase]]
[[Category: Phosphonate]]

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