Sandbox Reserved 1072: Difference between revisions
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==Other Ligands== | ==Other Ligands== | ||
Additional c-di-GMP and GTP molecules bind <scene name='69/694239/Flldgczwithc-di_and_allosteric/3'>allosterically</scene> to inhibitory sites on the exterior of the GGEEF domains, preventing the half sites from forming the active site and | Additional c-di-GMP and GTP molecules bind <scene name='69/694239/Flldgczwithc-di_and_allosteric/3'>allosterically</scene> to inhibitory sites on the exterior of the GGEEF domains, preventing the half sites from forming the active site and completing a reaction. The complete function of this binding is not yet well characterized. Weak product inhibition was observed when c-di-GMP bound allosterically, but the inhibition was so weak, it is possible that the c-di-GMP actually interacts with another unknown molecule at that site<sup>[9]</sup>. | ||
==See Also== | ==See Also== |