Vytorin: Difference between revisions
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Simvastatin interferes in the production of cholesterol and is a member of the statin medication family. As a group statins are known to lower a patient's LDL-C levels within their blood. Both patients with and without congestive heart disease (CHD) have experienced a reduction in their cardiovascular morbidity and mortality rights when prescribed medications in this family. <ref>http://e-lactancia.org/media/papers/StatinasFK-FundClinPhar2004.pdf</ref> Generally, simvastatin acts as a competitive inhibitor of HMG-CoA reductase which catalyzes the formation of mevalonate from HMG-CoA in the blood.<ref>https://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb2/part1/cholesterol.htm==Mechanism of Action</ref> This is further explained under mechanism of action. | Simvastatin interferes in the production of cholesterol and is a member of the statin medication family. As a group statins are known to lower a patient's LDL-C levels within their blood. Both patients with and without congestive heart disease (CHD) have experienced a reduction in their cardiovascular morbidity and mortality rights when prescribed medications in this family. <ref>http://e-lactancia.org/media/papers/StatinasFK-FundClinPhar2004.pdf</ref> Generally, simvastatin acts as a competitive inhibitor of HMG-CoA reductase which catalyzes the formation of mevalonate from HMG-CoA in the blood.<ref>https://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb2/part1/cholesterol.htm==Mechanism of Action</ref> This is further explained under mechanism of action. | ||
==Mechanism of Action== | |||
[[Image:Vhrm-8-415f2.jpg|thumb|left|500x500px|alt=A cartoon centipede reads books and types on a laptop.|The Wikipede edits ''[[Myriapoda]]''.]] | [[Image:Vhrm-8-415f2.jpg|thumb|left|500x500px|alt=A cartoon centipede reads books and types on a laptop.|The Wikipede edits ''[[Myriapoda]]''.]] | ||