Sandbox Reserved 1053: Difference between revisions

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{{Sandbox_Reserved_Butler_CH462_Sp2015_#}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE -->
==CzrA: A Zinc Dependent Transcriptional Regulator==
==CzrA: A Zinc Dependent Transcriptional Regulator==
<StructureSection load='2KJB' size='340' side='right' caption='The dimer CzrA' scene=''>
<StructureSection load='2KJB' size='340' frame='true' side='right' caption='The dimer CzrA' scene=''>
== Background ==
== Background ==
===Operon Overview===
===Operon Overview===
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===Czr Operon===
===Czr Operon===
The Chromosome Determined Zinc Responsible (Czr) operon acts as described above, with Czr A acting as the regulator protein. As such, Czr A is responsible for controlling the transcription of the rest of the operon and by extension, the transport of Zn <sup>2+</sup> out of the cell; the role of Czr A in the Czr operon is described in further detail as part of the explanation of biological function. In addition to being a component of an operon, Czr A is also considered to be a metal sensor protein. While the immediate function of Czr A is gene regulation, this serves the larger purpose of acting to maintain an appropriate concentration of Zn <sup>2+</sup> in the cell.
The Chromosome Determined Zinc Responsible (Czr) operon acts as described above, with Czr A acting as the regulator protein. As such, Czr A is responsible for controlling the transcription of the rest of the operon and by extension, the transport of Zn <sup>2+</sup> out of the cell; the role of Czr A in the Czr operon is described in further detail as part of the explanation of biological function. In addition to being a component of an operon, Czr A is also considered to be a metal sensor protein. While the immediate function of Czr A is gene regulation, this serves the larger purpose of acting to maintain an appropriate concentration of Zn <sup>2+</sup> in the cell.


   
   

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OCA, Ben Zercher, Geoffrey C. Hoops, Katelyn Baumer, Mary Liggett, Jakob Jozwiakowski