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==Crystal structures of homooligomers of collagen type IV. alpha4NC1== | |||
<StructureSection load='5nb1' size='340' side='right' caption='[[5nb1]], [[Resolution|resolution]] 2.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5nb1]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NB1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NB1 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nb1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nb1 OCA], [http://pdbe.org/5nb1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nb1 RCSB], [http://www.ebi.ac.uk/pdbsum/5nb1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nb1 ProSAT]</span></td></tr> | |||
[[ | </table> | ||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CO4A4_HUMAN CO4A4_HUMAN]] Benign familial hematuria;Autosomal dominant Alport syndrome;Autosomal recessive Alport syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CO4A4_HUMAN CO4A4_HUMAN]] Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Casino, P]] | [[Category: Casino, P]] | ||
[[Category: Marina, A]] | [[Category: Marina, A]] | ||
[[Category: Non-collagenous domain of collagen type iv. a principal structural component of basement membrane]] | |||
[[Category: Structural protein]] | |||
Revision as of 10:27, 12 September 2018
Crystal structures of homooligomers of collagen type IV. alpha4NC1Crystal structures of homooligomers of collagen type IV. alpha4NC1
Structural highlights
Disease[CO4A4_HUMAN] Benign familial hematuria;Autosomal dominant Alport syndrome;Autosomal recessive Alport syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Function[CO4A4_HUMAN] Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. |
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