Circadian clock protein: Difference between revisions

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Michal Harel (talk | contribs)
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<StructureSection load='1r8j' size='350' side='right' caption='Circadian clock protein KaiA (PDB entry [[1r8j]])' scene='53/536683/Cv/1'>
<StructureSection load='' size='350' side='right' caption='Circadian clock protein KaiA (PDB entry [[1r8j]])' scene='53/536683/Cv/1'>


'''Circadian clock proteins''' measure out the 24 hour circadian rhythm.  In cyanobacteria protein KaiA<ref>PMID:15007067</ref> stimulates KaiC<ref>PMID:15304218</ref> which adds phosphate groups to itself.  Then KaiC binds to KaiB<ref>PMID:15716247</ref> which inactivates KaiA and causes the number of phosphate groups on KaiC to drop slowly.  KaiB disconnects allowing KaiA to start the cycle again.<ref>PMID:11687489</ref>  For details of KaiC see [[Circadian Clock Protein KaiC]].
'''Circadian clock proteins''' measure out the 24 hour circadian rhythm.  In cyanobacteria protein KaiA<ref>PMID:15007067</ref> stimulates KaiC<ref>PMID:15304218</ref> which adds phosphate groups to itself.  Then KaiC binds to KaiB<ref>PMID:15716247</ref> which inactivates KaiA and causes the number of phosphate groups on KaiC to drop slowly.  KaiB disconnects allowing KaiA to start the cycle again.<ref>PMID:11687489</ref>  For details of KaiC see [[Circadian Clock Protein KaiC]].

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Michal Harel, Alexander Berchansky, Joel L. Sussman
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