5lgn: Difference between revisions
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==Thieno[3,2-b]pyrrole-5-carboxamides as Novel Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1: Compound 19== | ==Thieno[3,2-b]pyrrole-5-carboxamides as Novel Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1: Compound 19== | ||
<StructureSection load='5lgn' size='340' side='right' caption='[[5lgn]], [[Resolution|resolution]] 3.20Å' scene=''> | <StructureSection load='5lgn' size='340' side='right'caption='[[5lgn]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5lgn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LGN OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5lgn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LGN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5LGN FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6W0:~{N}-[3-(METHOXYMETHYL)PHENYL]-4-METHYL-THIENO[3,2-B]PYRROLE-5-CARBOXAMIDE'>6W0</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6W0:~{N}-[3-(METHOXYMETHYL)PHENYL]-4-METHYL-THIENO[3,2-B]PYRROLE-5-CARBOXAMIDE'>6W0</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KDM1A, AOF2, KDM1, KIAA0601, LSD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), RCOR1, KIAA0071, RCOR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5lgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lgn OCA], [http://pdbe.org/5lgn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lgn RCSB], [http://www.ebi.ac.uk/pdbsum/5lgn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lgn ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5lgn" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5lgn" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Lysine-specific histone demethylase 3D structures|Lysine-specific histone demethylase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Ciossani, G]] | [[Category: Ciossani, G]] | ||
[[Category: Mattevi, A]] | [[Category: Mattevi, A]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||