5te3: Difference between revisions

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'''Unreleased structure'''


The entry 5te3 is ON HOLD  until Paper Publication
==Crystal structure of Bos taurus opsin at 2.7 Angstrom==
 
<StructureSection load='5te3' size='340' side='right' caption='[[5te3]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
Authors: Gulati, S., Kiser, P.D., Palczewski, K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5te3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TE3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TE3 FirstGlance]. <br>
Description: Crystal structure of Bos taurus opsin at 2.7 Angstrom
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5te5|5te5]]</td></tr>
[[Category: Kiser, P.D]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5te3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5te3 OCA], [http://pdbe.org/5te3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5te3 RCSB], [http://www.ebi.ac.uk/pdbsum/5te3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5te3 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Gulati, S]]
[[Category: Gulati, S]]
[[Category: Kiser, P D]]
[[Category: Palczewski, K]]
[[Category: Palczewski, K]]
[[Category: Signaling protein]]

Revision as of 00:46, 16 March 2017

Crystal structure of Bos taurus opsin at 2.7 AngstromCrystal structure of Bos taurus opsin at 2.7 Angstrom

Structural highlights

5te3 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[OPSD_BOVIN] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).[1] [2]

References

  1. Nakamichi H, Okada T. Local peptide movement in the photoreaction intermediate of rhodopsin. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12729-34. Epub 2006 Aug 14. PMID:16908857
  2. Salom D, Lodowski DT, Stenkamp RE, Le Trong I, Golczak M, Jastrzebska B, Harris T, Ballesteros JA, Palczewski K. Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16123-8. Epub 2006 Oct 23. PMID:17060607

5te3, resolution 2.70Å

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