5m7b: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
==Blood group synthase AAGlyB in complex with UDP and cryoprotected with glycerol== | |||
<StructureSection load='5m7b' size='340' side='right' caption='[[5m7b]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5m7b]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5M7B FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zgf|3zgf]], [[3zgg|3zgg]], [[5m79|5m79]], [[5m7a|5m7a]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5m7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m7b OCA], [http://pdbe.org/5m7b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5m7b RCSB], [http://www.ebi.ac.uk/pdbsum/5m7b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5m7b ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/BGAT_HUMAN BGAT_HUMAN]] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Rocha, J]] | |||
[[Category: Royant, A]] | [[Category: Royant, A]] | ||
[[Category: | [[Category: Blood group synthase]] | ||
[[Category: Cis-ab mutant]] | |||
[[Category: Dual-specificity]] | |||
[[Category: Glycosyltransferase]] | |||
[[Category: Transferase]] |