5gn7: Difference between revisions

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'''Unreleased structure'''


The entry 5gn7 is ON HOLD  until Paper Publication
==Crystal structure of alternative oxidase from Trypanosoma brucei brucei complexed with cumarin derivative-17==
 
<StructureSection load='5gn7' size='340' side='right' caption='[[5gn7]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
Authors: Balogun, E.O., Inaoka, D.K., Shiba, T., Tsuge, T., May, B., Sato, T., Kido, Y., Takeshi, N., Aoki, T., Honma, T., Tanaka, A., Inoue, M., Matsuoka, S., Michels, P.A.M., Watanabe, Y., Moore, A.L., Harada, S., Kita, K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[5gn7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trybb Trybb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GN7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GN7 FirstGlance]. <br>
Description: Crystal structure of alternative oxidase from Trypanosoma brucei brucei complexed with cumarin derivative-17
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6XZ:4-[[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-7,8-bis(oxidanyl)chromen-2-one'>6XZ</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=OH:HYDROXIDE+ION'>OH</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vv9|3vv9]], [[5gn5|5gn5]], [[5gn6|5gn6]], [[5gn9|5gn9]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AOX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5702 TRYBB])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gn7 OCA], [http://pdbe.org/5gn7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gn7 RCSB], [http://www.ebi.ac.uk/pdbsum/5gn7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gn7 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/AOX_TRYBB AOX_TRYBB]] Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.  
__TOC__
</StructureSection>
[[Category: Trybb]]
[[Category: Aoki, T]]
[[Category: Balogun, E O]]
[[Category: Harada, S]]
[[Category: Honma, T]]
[[Category: Honma, T]]
[[Category: Tsuge, T]]
[[Category: Inaoka, D K]]
[[Category: Inoue, M]]
[[Category: Kido, Y]]
[[Category: Kita, K]]
[[Category: Matsuoka, S]]
[[Category: Matsuoka, S]]
[[Category: May, B]]
[[Category: Michels, P A.M]]
[[Category: Moore, A L]]
[[Category: Sato, T]]
[[Category: Sato, T]]
[[Category: Shiba, T]]
[[Category: Shiba, T]]
[[Category: Inaoka, D.K]]
[[Category: Takeshi, N]]
[[Category: Kita, K]]
[[Category: Tanaka, A]]
[[Category: Moore, A.L]]
[[Category: Tsuge, T]]
[[Category: Michels, P.A.M]]
[[Category: Watanabe, Y]]
[[Category: Watanabe, Y]]
[[Category: Balogun, E.O]]
[[Category: African trypanosome]]
[[Category: Tanaka, A]]
[[Category: Alternative oxidase]]
[[Category: Harada, S]]
[[Category: Drug]]
[[Category: Takeshi, N]]
[[Category: Inhibitor]]
[[Category: Inoue, M]]
[[Category: Oxido-reductase]]
[[Category: May, B]]
[[Category: Transferase]]
[[Category: Aoki, T]]
[[Category: Kido, Y]]

Revision as of 07:34, 16 November 2017

Crystal structure of alternative oxidase from Trypanosoma brucei brucei complexed with cumarin derivative-17Crystal structure of alternative oxidase from Trypanosoma brucei brucei complexed with cumarin derivative-17

Structural highlights

5gn7 is a 4 chain structure with sequence from Trybb. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:AOX (TRYBB)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[AOX_TRYBB] Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.

5gn7, resolution 3.20Å

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OCA
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