Tumor necrosis factor receptor: Difference between revisions

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<StructureSection load='1ext' size='340' side='right' caption='Structure of human TNFR extracellular domain complex with sulfate and Mg+2 ion (green) (PDB code [[1ext]]).' scene=''>
<StructureSection load='1ext' size='450' side='right' caption='Structure of human TNFR extracellular domain complex with sulfate and Mg+2 ion (green) (PDB code [[1ext]]).' scene='59/590824/Cv/2'>
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== Function ==
== Function ==
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== Structural highlights ==
== Structural highlights ==
The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains (CRD).  The CRD domains are ca. 40 amino-acid long and contain 4-6 cysteine residues.  The CRDs are involved in binding of TNF<ref>PMID:8939750</ref>.
The extracellular domain of TNFR contains 2 to 6 cysteine-rich domains (CRD).  The <scene name='59/590824/Cv/3'>CRD domains are ca. 40 amino-acid long and contain 4-6 cysteine residues</scene>.  The CRDs are involved in binding of TNF<ref>PMID:8939750</ref>.
</StructureSection>
</StructureSection>


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Michal Harel, Alexander Berchansky