Sandbox Reserved 1061: Difference between revisions
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{{Sandbox_Reserved_Butler_CH462_Sp2015_#}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | [[Image:Example.jpg]]{{Sandbox_Reserved_Butler_CH462_Sp2015_#}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
== | ==Human Caspase-6== | ||
<StructureSection load=' | <StructureSection load='4FXO' size='340' side='right' caption='Caption for this structure' scene=''> | ||
This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page ''''''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
== Biological Function == | == Biological Function == | ||
Caspase-6 is a protease involved in '''apoptosis'''. It is most notably involved in neurodegenerative diseases, such as Alzheimer's disease and dementia. | |||
== Structural Overview == | |||
== | === Inactive State === | ||
When the protein is in the inactive state it is a '''Homotetramer'''. | |||
=== Active State === | |||
Caspase-6 enters | |||
== Mechanism of Action == | == Mechanism of Action == | ||
Revision as of 17:06, 28 February 2017
| This Sandbox is Reserved from 02/09/2015, through 05/31/2016 for use in the course "CH462: Biochemistry 2" taught by Geoffrey C. Hoops at the Butler University. This reservation includes Sandbox Reserved 1051 through Sandbox Reserved 1080. |
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Human Caspase-6Human Caspase-6
This is a default text for your page '. Click above on edit this page' to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue. Biological FunctionCaspase-6 is a protease involved in apoptosis. It is most notably involved in neurodegenerative diseases, such as Alzheimer's disease and dementia. Structural OverviewInactive StateWhen the protein is in the inactive state it is a Homotetramer. Active StateCaspase-6 enters Mechanism of ActionZinc Ligand(s)Other LigandsThis is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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ReferencesReferences
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644