IGF1: Difference between revisions

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Revision as of 18:24, 27 January 2017 view source Maxime Julliot (talk \| contribs) 37 edits No edit summary ← Older edit		Revision as of 18:36, 27 January 2017 view source Maxime Julliot (talk \| contribs) 37 edits No edit summary Newer edit →
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	IGF-1 docks IGFBP with a series of polar and non-polar interactions all along its binding site. For instance, when IGF-1 binds IGFBP-4, <scene name='75/751772/Igf-1_docking_on_igfbp/1'>VAL48 matches PHE16</scene>. Both are hydrophobic residues. This mechanism can also be applied to all interactions between proteins of the insulin protein family such as the docking of IGF-2 in IGFBP-5.		IGF-1 docks IGFBP with a series of polar and non-polar interactions all along its binding site. For instance, when IGF-1 binds IGFBP-4, <scene name='75/751772/Igf-1_docking_on_igfbp/1'>VAL48 matches PHE16</scene>. Both are hydrophobic residues. This mechanism can also be applied to all interactions between proteins of the insulin protein family such as the docking of IGF-2 in IGFBP-5.