3nfa: Difference between revisions
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==Structural basis for a new mechanism of inhibition of HIV integrase identified by fragment screening and structure based design== | ==Structural basis for a new mechanism of inhibition of HIV integrase identified by fragment screening and structure based design== | ||
<StructureSection load='3nfa' size='340' side='right' caption='[[3nfa]], [[Resolution|resolution]] 1.95Å' scene=''> | <StructureSection load='3nfa' size='340' side='right'caption='[[3nfa]], [[Resolution|resolution]] 1.95Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3nfa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFA OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[3nfa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3NFA FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CBJ:6-[(5-BROMO-2,3-DIOXO-2,3-DIHYDRO-1H-INDOL-1-YL)METHYL]-2,3-DIHYDRO-1,4-BENZODIOXINE-5-CARBOXYLIC+ACID'>CBJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CBJ:6-[(5-BROMO-2,3-DIOXO-2,3-DIHYDRO-1H-INDOL-1-YL)METHYL]-2,3-DIHYDRO-1,4-BENZODIOXINE-5-CARBOXYLIC+ACID'>CBJ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bhl|1bhl]], [[1bi4|1bi4]], [[1biu|1biu]], [[1ex4|1ex4]], [[1k6y|1k6y]], [[3nf6|3nf6]], [[3nf7|3nf7]], [[3nf8|3nf8]], [[3nf9|3nf9]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bhl|1bhl]], [[1bi4|1bi4]], [[1biu|1biu]], [[1ex4|1ex4]], [[1k6y|1k6y]], [[3nf6|3nf6]], [[3nf7|3nf7]], [[3nf8|3nf8]], [[3nf9|3nf9]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3nfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nfa OCA], [http://pdbe.org/3nfa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nfa RCSB], [http://www.ebi.ac.uk/pdbsum/3nfa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nfa ProSAT]</span></td></tr> | ||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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==See Also== | ==See Also== | ||
*[[Retroviral | *[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Deadman, J J]] | [[Category: Deadman, J J]] | ||
[[Category: Newman, J]] | [[Category: Newman, J]] | ||