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==Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftobiprole== | |||
<StructureSection load='5tx9' size='340' side='right' caption='[[5tx9]], [[Resolution|resolution]] 1.68Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5tx9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TX9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TX9 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RB6:(2R)-2-[(1R)-1-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-2-oxoethyl]-5-({2-oxo-1-[(3R)-pyrrolidin-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}methyl)-3,6-dihydro-2H-1,3-thiazine-4-carboxylic+acid'>RB6</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tx9 OCA], [http://pdbe.org/5tx9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tx9 RCSB], [http://www.ebi.ac.uk/pdbsum/5tx9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tx9 ProSAT]</span></td></tr> | ||
</table> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Alexander, J A.N]] | |||
[[Category: Strynadka, N C.J]] | |||
[[Category: Antibiotic]] | |||
[[Category: Hydrolase]] | |||
[[Category: Hydrolase - antibiotic complex]] |
Revision as of 08:24, 16 May 2018
Crystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftobiproleCrystal structure of S. aureus penicillin binding protein 4 (PBP4) mutant (E183A, F241R) in complex with ceftobiprole
Structural highlights
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