5tq6: Difference between revisions

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 ==Design and Synthesis of a pan-JAK Kinase Inhibitor Clinical Candidate (PF-06263276) Suitable for Inhaled and Topical Delivery for the Treatment of Inflammatory Diseases of the Lungs and Skin==
-<StructureSection load='5tq6' size='340' side='right' caption='[[5tq6]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
+<StructureSection load='5tq6' size='340' side='right'caption='[[5tq6]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5tq6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TQ6 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5tq6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5TQ6 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7GV:{(3R,4R)-4-METHYL-3-[METHYL(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]PIPERIDIN-1-YL}(PYRROLIDIN-1-YL)METHANONE'>7GV</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7GV:{(3R,4R)-4-METHYL-3-[METHYL(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]PIPERIDIN-1-YL}(PYRROLIDIN-1-YL)METHANONE'>7GV</scene></td></tr>
 <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
 <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5tq8|5tq8]], [[5tq7|5tq7]], [[5tq5|5tq5]], [[5tq4|5tq4]], [[5tq3|5tq3]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">JAK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
 <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tq6 OCA], [http://pdbe.org/5tq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tq6 RCSB], [http://www.ebi.ac.uk/pdbsum/5tq6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tq6 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5tq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tq6 OCA], [http://pdbe.org/5tq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tq6 RCSB], [http://www.ebi.ac.uk/pdbsum/5tq6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tq6 ProSAT]</span></td></tr>
 </table>
 == Disease ==
@@ Line 23: / Line 24: @@
 </div>
 <div class="pdbe-citations 5tq6" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Janus kinase 3D structures|Janus kinase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
+[[Category: Human]]
+[[Category: Large Structures]]
 [[Category: Non-specific protein-tyrosine kinase]]
 [[Category: Chrencik, J]]