SAICAR synthetase: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
SAI structure shows <scene name='74/749400/Cv/2'>two domains</scene>. The <scene name='74/749400/Cv/9'>active site is located in a hydrophilic tunnel</scene> between the 2 domains and contains <scene name='74/749400/Cv/4'>ADP</scene>, <scene name='74/749400/Cv/6'>aspartic acid</scene> and <scene name='74/749400/Cv/7'>aminoimidazole-ribonucleotide (AIR)</scene><ref>PMID:24598753</ref>. {{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}. Water molecules shown as red spheres. | SAI structure shows <scene name='74/749400/Cv/2'>two domains</scene>. The <scene name='74/749400/Cv/9'>active site is located in a hydrophilic tunnel</scene> between the 2 domains and contains <scene name='74/749400/Cv/4'>ADP</scene>, <scene name='74/749400/Cv/6'>aspartic acid</scene> and <scene name='74/749400/Cv/7'>aminoimidazole-ribonucleotide (AIR)</scene><ref>PMID:24598753</ref>. Residues are colored according to {{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}. Water molecules shown as red spheres. | ||
*<scene name='74/749400/Cv/3'>Surface representation of hydrophilic tunnel</scene>. | *<scene name='74/749400/Cv/3'>Surface representation of hydrophilic tunnel</scene>. | ||
*<scene name='74/749400/Cv/5'>Mg coordination site</scene>. | *<scene name='74/749400/Cv/5'>Mg coordination site</scene>. | ||