2ypd: Difference between revisions
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==Crystal structure of the Jumonji domain of human Jumonji domain containing 1C protein== | ==Crystal structure of the Jumonji domain of human Jumonji domain containing 1C protein== | ||
<StructureSection load='2ypd' size='340' side='right' caption='[[2ypd]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='2ypd' size='340' side='right'caption='[[2ypd]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ypd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YPD FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ypd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YPD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YPD FirstGlance]. <br> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Berridge, G]] | [[Category: Berridge, G]] | ||
Revision as of 17:08, 25 December 2019
Crystal structure of the Jumonji domain of human Jumonji domain containing 1C proteinCrystal structure of the Jumonji domain of human Jumonji domain containing 1C protein
Structural highlights
Function[JHD2C_HUMAN] Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity). |
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