UvrABC: Difference between revisions
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<StructureSection load='3pih' size=' | <StructureSection load='3pih' size='450' side='right' caption='UvrA complex with DNA, pyrophosphate and Zn+2 ion (grey) [[3pih]]' scene='' > | ||
== Function == | == Function == | ||
'''UvrABC''' endonuclease is an ''E. coli'' enzyme complex involved in DNA repair. UvrABC removes 12 nucleotides around a DNA mutation replacing them with the correct one<ref>PMID:11004168</ref>.<br /> | '''UvrABC''' endonuclease is an ''E. coli'' enzyme complex involved in DNA repair. UvrABC removes 12 nucleotides around a DNA mutation replacing them with the correct one<ref>PMID:11004168</ref>.<br /> | ||
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== Structural highlights == | == Structural highlights == | ||
UvrA contains several domains: UvrB-binding, DNA-binding and two ATP-binding domains<ref>PMID:21240268</ref>. | UvrA contains several domains: <scene name='53/536710/Cv/1'>UvrB-binding, DNA-binding and two ATP-binding domains</scene><ref>PMID:21240268</ref>. | ||
</StructureSection> | </StructureSection> | ||
==3D structures of UvrABC== | ==3D structures of UvrABC== | ||