5kzi: Difference between revisions
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==Crystal structure of human Pim-1 kinase in complex with an imidazopyridazine inhibitor.== | ==Crystal structure of human Pim-1 kinase in complex with an imidazopyridazine inhibitor.== | ||
<StructureSection load='5kzi' size='340' side='right' caption='[[5kzi]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='5kzi' size='340' side='right'caption='[[5kzi]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5kzi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KZI OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[5kzi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KZI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KZI FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6YN:~{N}-[4-[(3~{S})-3-AZANYLPIPERIDIN-1-YL]PYRIDIN-3-YL]-2-[2,6-BIS(FLUORANYL)PHENYL]IMIDAZO[1,5-B]PYRIDAZIN-7-AMINE'>6YN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6YN:~{N}-[4-[(3~{S})-3-AZANYLPIPERIDIN-1-YL]PYRIDIN-3-YL]-2-[2,6-BIS(FLUORANYL)PHENYL]IMIDAZO[1,5-B]PYRIDAZIN-7-AMINE'>6YN</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5kzi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kzi OCA], [http://pdbe.org/5kzi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kzi RCSB], [http://www.ebi.ac.uk/pdbsum/5kzi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kzi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Mohr, C]] | [[Category: Mohr, C]] | ||