5tpk: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 5tpk is ON HOLD  until Paper Publication
+==Crystal Structure of Mouse Protocadherin-15 EC7-8 V875A==
+<StructureSection load='5tpk' size='340' side='right' caption='[[5tpk]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5tpk]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TPK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TPK FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tpk OCA], [http://pdbe.org/5tpk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tpk RCSB], [http://www.ebi.ac.uk/pdbsum/5tpk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tpk ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/PCD15_MOUSE PCD15_MOUSE]] Defects in Pcdh15 are the cause of the Ames waltzer (av) phenotype. It is characterized by deafness and a balance disorder, associated with the degeneration of inner ear neuroepithelia.
+== Function ==
+[[http://www.uniprot.org/uniprot/PCD15_MOUSE PCD15_MOUSE]] Calcium-dependent cell-adhesion protein. Required for inner ear neuroepithelial cell elaboration and cochlear function. Probably involved in the maintenance of normal retinal function.
+__TOC__
+</StructureSection>
+[[Category: Chen, C]]
+[[Category: Sotomayor, M]]
+[[Category: Adhesion]]
+[[Category: Calcium-binding protein]]
+[[Category: Cell adhesion]]
+[[Category: Hearing]]
+[[Category: Mechanotransduction]]