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==Leishmania major N-myristoyltransferase in complex with a quinoline inhibitor (compound 26).== | |||
<StructureSection load='5g21' size='340' side='right' caption='[[5g21]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5g21]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G21 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5G21 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene>, <scene name='pdbligand=YN4:ETHYL+4-[(2-CYANOETHYL)SULFANYL]-6-{[6-(PIPERAZIN-1-YL)'>YN4</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5g1z|5g1z]], [[5g20|5g20]], [[5g22|5g22]]</td></tr> | ||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycylpeptide_N-tetradecanoyltransferase Glycylpeptide N-tetradecanoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.97 2.3.1.97] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5g21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g21 OCA], [http://pdbe.org/5g21 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5g21 RCSB], [http://www.ebi.ac.uk/pdbsum/5g21 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5g21 ProSAT]</span></td></tr> | |||
[[Category: Brannigan, J | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/Q4Q5S8_LEIMA Q4Q5S8_LEIMA]] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Glycylpeptide N-tetradecanoyltransferase]] | |||
[[Category: Bell, A S]] | |||
[[Category: Brannigan, J A]] | |||
[[Category: Goncalves, V]] | [[Category: Goncalves, V]] | ||
[[Category: Laporte, A]] | [[Category: Laporte, A]] | ||
[[Category: | [[Category: Leatherbarrow, R J]] | ||
[[Category: Roberts, S M]] | |||
[[Category: Tate, E W]] | |||
[[Category: Wilkinson, A J]] | |||
[[Category: Drug design]] | |||
[[Category: Inhibitor]] | |||
[[Category: Malaria]] | |||
[[Category: Myristoylation]] | |||
[[Category: Quinoline]] | |||
[[Category: Transferase]] | |||
Revision as of 20:34, 10 March 2017
Leishmania major N-myristoyltransferase in complex with a quinoline inhibitor (compound 26).Leishmania major N-myristoyltransferase in complex with a quinoline inhibitor (compound 26).
Structural highlights
Function[Q4Q5S8_LEIMA] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity). |
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