5fdx: Difference between revisions

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<StructureSection load='5fdx' size='340' side='right' caption='[[5fdx]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='5fdx' size='340' side='right' caption='[[5fdx]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fdx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FDX FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fdx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FDX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FDX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5X1:3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-~{N}-[(4~{R})-4-METHYL-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLIN-7-YL]-5-(TRIFLUOROMETHYL)BENZAMIDE'>5X1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5X1:3-[(4-METHYLPIPERAZIN-1-YL)METHYL]-~{N}-[(4~{R})-4-METHYL-2-PYRIMIDIN-5-YL-3,4-DIHYDRO-1~{H}-ISOQUINOLIN-7-YL]-5-(TRIFLUOROMETHYL)BENZAMIDE'>5X1</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdx OCA], [http://pdbe.org/5fdx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fdx RCSB], [http://www.ebi.ac.uk/pdbsum/5fdx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fdx OCA], [http://pdbe.org/5fdx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fdx RCSB], [http://www.ebi.ac.uk/pdbsum/5fdx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fdx ProSAT]</span></td></tr>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith, C H]]
[[Category: BARTUAL, S G]]
[[Category: Bartual, S G]]
[[Category: BOUNTRA, C]]
[[Category: BULLOCK, A]]
[[Category: Borkowska, O]]
[[Category: Borkowska, O]]
[[Category: Bountra, C]]
[[Category: Bullock, A]]
[[Category: Burgess-Brown, N]]
[[Category: Burgess-Brown, N]]
[[Category: Chaikuad, A]]
[[Category: Chaikuad, A]]
[[Category: Chalk, R]]
[[Category: Chalk, R]]
[[Category: DELFT, F VON]]
[[Category: Delft, F von]]
[[Category: DING, K]]
[[Category: Ding, K]]
[[Category: Edwards, A M]]
[[Category: Edwards, A M]]
[[Category: KUPINSKA, K]]
[[Category: Kopec, J]]
[[Category: Kopec, J]]
[[Category: Kupinska, K]]
[[Category: Mahajan, P]]
[[Category: Mahajan, P]]
[[Category: Mukhopadhyay, S]]
[[Category: Mukhopadhyay, S]]
[[Category: Newman, J]]
[[Category: Newman, J]]
[[Category: PINKAS, D M]]
[[Category: Pinkas, D M]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Sorell, F]]
[[Category: Sorell, F]]
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[[Category: Tallant, C]]
[[Category: Tallant, C]]
[[Category: Talon, R]]
[[Category: Talon, R]]
[[Category: WANG, Z]]
[[Category: Wang, Z]]
[[Category: Williams, E]]
[[Category: Williams, E]]
[[Category: Ddr1 kinase]]
[[Category: Ddr1 kinase]]

Revision as of 10:22, 13 December 2017

Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.Structure of DDR1 receptor tyrosine kinase in complex with D2164 inhibitor at 2.65 Angstroms resolution.

Structural highlights

5fdx is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE (HUMAN)
Activity:Receptor protein-tyrosine kinase, with EC number 2.7.10.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

5fdx, resolution 2.65Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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