5f6c: Difference between revisions

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-'''Unreleased structure'''
-The entry 5f6c is ON HOLD  until Paper Publication
+==The structure of E. coli RNase E catalytically inactive mutant with RNA bound==
+<StructureSection load='5f6c' size='340' side='right' caption='[[5f6c]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-Authors: Bandyra, K.J., Luisi, B.F.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5f6c]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F6C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F6C FirstGlance]. <br>
-Description: The structure of E. coli RNase E catalytically inactive mutant with RNA bound
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_E Ribonuclease E], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.12 3.1.26.12] </span></td></tr>
-[[Category: Luisi, B.F]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f6c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f6c OCA], [http://pdbe.org/5f6c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f6c RCSB], [http://www.ebi.ac.uk/pdbsum/5f6c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5f6c ProSAT]</span></td></tr>
-[[Category: Bandyra, K.J]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/RNE_ECOLI RNE_ECOLI]] Matures 5S rRNA from its precursors from all the rRNA genes. It also cleaves RNA I, a molecule that controls the replication of colE1 plasmid DNA. It is the major endoribonuclease participating in mRNA turnover in E.coli. It initiates the decay of RNAs by cutting them internally near their 5'-end. It is able to remove poly(A) tails by an endonucleolytic process.
+__TOC__
+</StructureSection>
+[[Category: Ribonuclease E]]
+[[Category: Bandyra, K J]]
+[[Category: Luisi, B F]]
+[[Category: Hydrolase]]
+[[Category: Hydrolytic mechanism]]
+[[Category: Regulatory rna]]
+[[Category: Ribonuclease]]