Zbtb7: Difference between revisions
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==Introduction== | ==Introduction== | ||
Zbtb7 which was originally named as Pokemon (POK erythroid myeloid ontogenic factor) is a gene which plays a critical role in development, cellular differentiation and oncogenesis and has a crucial role in interacting with other POK family proteins.The gene was discovered in 2005 by the team of scientists from Memorial Sloan-Kettering Cancer Center, New York and Institute of Cancer Research, London. Scientists have reported the transcriptional repressor Pokemon as a critical factor in oncogenesis.[1] | Zbtb7 which was originally named as Pokemon (POK erythroid myeloid ontogenic factor) is a gene which plays a critical role in development, cellular differentiation and oncogenesis and has a crucial role in interacting with other POK family proteins.The gene was discovered in 2005 by the team of scientists from Memorial Sloan-Kettering Cancer Center, New York and Institute of Cancer Research, London. Scientists have reported the transcriptional repressor Pokemon as a critical factor in oncogenesis.[1] <Structure load='2NN2' size='350' frame='true' align='right'caption='BTB-zinc finger (BTB-ZF) proteins are transcription regulators with roles in development, differentiation, and oncogenesis. In these proteins, the BTB domain (also known as the POZ domain) is a protein-protein interaction motif that contains a dimerization interface, a possible oligomerization surface' | ||
== Function == | == Function == | ||