Pikachurin: Difference between revisions
Rajesh Pal (talk | contribs) No edit summary |
Rajesh Pal (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
==Introduction== | |||
Synapse formation is very important for mammalian CNS to function properly. Information is transferred from photoreceptors present in the eye to bipolar and horizontal cells at the specialized synapse known as ribbon synapse.Pikachurin is an extracellular retinal protein which helps in precise interaction and signal transmission between ribbon synapse and bipolar dendrites. | |||
== Function == | == Function == | ||
Pikachurin protein has a dual function of photoreceptor visual synapse formation and visual perception. | |||
[[Image:nn0808-857-F1.jpg]] | |||
== Disease == | == Disease == | ||
| Line 13: | Line 17: | ||
2)http://www.uniprot.org/uniprot/Q63HQ2 | 2)http://www.uniprot.org/uniprot/Q63HQ2 | ||
<references/> | <references/> | ||
3)Sato S1, Omori Y, Katoh K, Kondo M, Kanagawa M, Miyata K, Funabiki K, Koyasu T, Kajimura N, Miyoshi T, Sawai H, Kobayashi K, Tani A, Toda T, Usukura J, Tano Y, Fujikado T, Furukawa T.Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation.Nat Neurosci. 2008 Aug;11(8):923-31. doi: 10.1038/nn.2160. Epub 2008 Jul 20. | |||