5lzk: Difference between revisions

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-'''Unreleased structure'''
-The entry 5lzk is ON HOLD
+==Structure of the domain of unknown function DUF1669 from human FAM83B==
+<StructureSection load='5lzk' size='340' side='right' caption='[[5lzk]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
-Authors: Pinkas, D.M., Bufton, J.C., Williams, E.P., Shrestha, L., Burgess-Brown, N.A., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A., Structural Genomics Consortium (SGC)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5lzk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5LZK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5LZK FirstGlance]. <br>
-Description: Structure of the domain of unknown function DUF1669 from human FAM83B
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5lzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5lzk OCA], [http://pdbe.org/5lzk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5lzk RCSB], [http://www.ebi.ac.uk/pdbsum/5lzk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5lzk ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN]] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Arrowsmith, C H]]
+[[Category: Bountra, C]]
+[[Category: Bufton, J C]]
 [[Category: Bullock, A]]
-[[Category: Burgess-Brown, N.A]]
+[[Category: Burgess-Brown, N A]]
-[[Category: Pinkas, D.M]]
+[[Category: Delft, F von]]
-[[Category: Bountra, C]]
+[[Category: Edwards, A M]]
-[[Category: Williams, E.P]]
+[[Category: Pinkas, D M]]
-[[Category: Arrowsmith, C.H]]
+[[Category: Structural genomic]]
 [[Category: Shrestha, L]]
-[[Category: Von Delft, F]]
+[[Category: Williams, E P]]
-[[Category: Bufton, J.C]]
+[[Category: Domain of unknown function]]
-[[Category: Edwards, A.M]]
+[[Category: Sgc]]
-[[Category: Structural Genomics Consortium (Sgc)]]