Tryptophan RNA-binding attenuation protein

Function Tryptophan RNA-binding attenuation protein (TRAP) is a tryptophan-activated RNA-binding protein which regulates the expression of the tryptophan biosynthesis genes. Down regulation of Trp biosynthesis is observed upon binding of 11 Trp to TRAP. Structural highlights TRAP is composed of 11 identical subunits arranged in a symmetrical ring. Tryptophan is bound to TRAP by mostly non-polar residues.

spinqualitylabelsall models Structure of tryptophan RNA-binding attenuation protein complex with Trp (PDB code 2exs). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of tryptophan RNA-binding attenuation protein3D Structures of tryptophan RNA-binding attenuation protein

Updated on 27-November-2016

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• Tryptophan RNA-binding attenuation protein
  • 3aqd – GsTRAP – Geobacillus stearothermophilus
    
• Tryptophan RNA-binding attenuation protein binary complex with Trp
  • 2zdo, 2exs, 2ext, 2zcz, 2zd0, 3zzs, 1qaw – GsTRAP + Trp
    
  • 5eew, 5eex, 5eey, 5eez, 5ef0, 5ef1, 5ef2, 5ef3 – GsTRAP + Trp – radiation damage
    
  • 1wap, 3zzq – BsTRAP + Trp – Bacillus subtilis
    
  • 4b27 – BsTRAP (mutant) + Trp
    
  • 3zte – TRAP + Trp – Bacillus licheniformis
    
  • 3zzl – TRAP + Trp – Bacillus halodurans
    
• Tryptophan RNA-binding attenuation protein ternary complex with Trp
  • 1c9s, 1gtf, 1gtn, 1utd, 4v4f – GsTRAP + RNA + Trp
    
  • 2zp8, 2zp9 – GsTRAP + TRAP inhibitory protein + Trp