Thymidylate kinase: Difference between revisions

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== Relevance ==
== Relevance ==
The TMK inhibitor azido-dTMP (AZTP) is an HIV AZT prodrug metabolite<ref>PMID:15722537</ref>.  Inhibitors of TMK are used as antibacterial agents<ref>PMID:23043329</ref>.
The TMK inhibitor azido-dTMP (AZTP) is an HIV AZT prodrug metabolite<ref>PMID:15722537</ref>.  Inhibitors of TMK are used as antibacterial agents<ref>PMID:23043329</ref>.
== Structural highlights ==
The active site of TMK contains thymidine, ADP and Mg+2 ion<ref>PMID:11071809</ref>.


== 3D Structures of thymidylate kinase ==
== 3D Structures of thymidylate kinase ==

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Michal Harel, Alexander Berchansky, Joel L. Sussman