4ot6: Difference between revisions
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==Crystal structure of BTK kinase domain complexed with 4-Methanesulfonyl-N-(3-{8-[4-(morpholine-4-carbonyl)-phenylamino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-benzamide== | ==Crystal structure of BTK kinase domain complexed with 4-Methanesulfonyl-N-(3-{8-[4-(morpholine-4-carbonyl)-phenylamino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-benzamide== | ||
<StructureSection load='4ot6' size='340' side='right' caption='[[4ot6]], [[Resolution|resolution]] 2.05Å' scene=''> | <StructureSection load='4ot6' size='340' side='right'caption='[[4ot6]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ot6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OT6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OT6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4ot6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OT6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OT6 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2V1:4-(METHYLSULFONYL)-N-[3-(8-{[4-(MORPHOLIN-4-YLCARBONYL)PHENYL]AMINO}IMIDAZO[1,2-A]PYRAZIN-6-YL)PHENYL]BENZAMIDE'>2V1</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2V1:4-(METHYLSULFONYL)-N-[3-(8-{[4-(MORPHOLIN-4-YLCARBONYL)PHENYL]AMINO}IMIDAZO[1,2-A]PYRAZIN-6-YL)PHENYL]BENZAMIDE'>2V1</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ot5|4ot5]], [[4otq|4otq]], [[4otr|4otr]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ot5|4ot5]], [[4otq|4otq]], [[4otr|4otr]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BTK, AGMX1, ATK, BPK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_protein-tyrosine_kinase Non-specific protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.2 2.7.10.2] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ot6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ot6 OCA], [http://pdbe.org/4ot6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ot6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ot6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ot6 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ot6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ot6 OCA], [http://pdbe.org/4ot6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ot6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ot6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ot6 ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
[[Category: Kuglstatter, A]] | [[Category: Kuglstatter, A]] | ||
[[Category: Wong, A]] | [[Category: Wong, A]] | ||
[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||