4whk: Difference between revisions
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==A New Class of Peptidomimetics Targeting the Polo-box Domain of Polo-like kinase 1== | ==A New Class of Peptidomimetics Targeting the Polo-box Domain of Polo-like kinase 1== | ||
<StructureSection load='4whk' size='340' side='right' caption='[[4whk]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='4whk' size='340' side='right'caption='[[4whk]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4whk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WHK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WHK FirstGlance]. <br> | <table><tr><td colspan='2'>[[4whk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WHK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WHK FirstGlance]. <br> | ||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=56A:3-(8-PHENYLOCTYL)-L-HISTIDINE'>56A</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene>, <scene name='pdbligand=YAC:(4Z)-6-OXO-6-PHENYLHEX-4-ENOIC+ACID'>YAC</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=56A:3-(8-PHENYLOCTYL)-L-HISTIDINE'>56A</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene>, <scene name='pdbligand=YAC:(4Z)-6-OXO-6-PHENYLHEX-4-ENOIC+ACID'>YAC</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4whh|4whh]], [[4whl|4whl]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4whh|4whh]], [[4whl|4whl]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PLK1, PLK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Polo_kinase Polo kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.21 2.7.11.21] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Polo_kinase Polo kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.21 2.7.11.21] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4whk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4whk OCA], [http://pdbe.org/4whk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4whk RCSB], [http://www.ebi.ac.uk/pdbsum/4whk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4whk ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4whk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4whk OCA], [http://pdbe.org/4whk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4whk RCSB], [http://www.ebi.ac.uk/pdbsum/4whk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4whk ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | |||
[[Category: Large Structures]] | |||
[[Category: Polo kinase]] | [[Category: Polo kinase]] | ||
[[Category: Ahn, M J]] | [[Category: Ahn, M J]] | ||