4f96: Difference between revisions

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 ==Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP==
-<StructureSection load='4f96' size='340' side='right' caption='[[4f96]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
+<StructureSection load='4f96' size='340' side='right'caption='[[4f96]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4f96]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_hygroscopicus_subsp._limoneus"_shibata_et_al._1973 "streptomyces hygroscopicus subsp. limoneus" shibata et al. 1973]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F96 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F96 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4f96]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_hygroscopicus_subsp._limoneus Streptomyces hygroscopicus subsp. limoneus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F96 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vdm|3vdm]], [[3vdn|3vdn]], [[4f97|4f97]], [[4f9f|4f9f]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f96 OCA], [https://pdbe.org/4f96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f96 RCSB], [https://www.ebi.ac.uk/pdbsum/4f96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f96 ProSAT]</span></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vldE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=264445 "Streptomyces hygroscopicus subsp. limoneus" Shibata et al. 1973])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f96 OCA], [http://pdbe.org/4f96 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4f96 RCSB], [http://www.ebi.ac.uk/pdbsum/4f96 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4f96 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/VLDE_STRHL VLDE_STRHL] Involved in the biosynthesis of the antifungal agent validamycin A (PubMed:16725283). Catalyzes the condensation between GDP-valienol and validamine 7-phosphate via a nonglycosidic C-N bond formation to yield validoxylamine A 7'-phosphate (PubMed:21766819).<ref>PMID:16725283</ref> <ref>PMID:21766819</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 22: @@
 __TOC__
 </StructureSection>
-[[Category: Streptomyces hygroscopicus subsp. limoneus shibata et al. 1973]]
+[[Category: Large Structures]]
-[[Category: Almabruk, K H]]
+[[Category: Streptomyces hygroscopicus subsp. limoneus]]
-[[Category: Asamizu, S]]
+[[Category: Almabruk KH]]
-[[Category: Cavalier, M C]]
+[[Category: Asamizu S]]
-[[Category: Lee, Y H]]
+[[Category: Cavalier MC]]
-[[Category: Mahmud, T]]
+[[Category: Lee Y-H]]
-[[Category: Neau, D]]
+[[Category: Mahmud T]]
-[[Category: Yim, Y S]]
+[[Category: Neau D]]
-[[Category: Transferase]]
+[[Category: Yim Y-S]]
-[[Category: Twin rossman fold]]