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==Crystal structure of the mutant I96T of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate== | ==Crystal structure of the mutant I96T of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with 6-azauridine 5'-monophosphate== | ||
<StructureSection load='3pbv' size='340' side='right' caption='[[3pbv]], [[Resolution|resolution]] 1.30Å' scene=''> | <StructureSection load='3pbv' size='340' side='right'caption='[[3pbv]], [[Resolution|resolution]] 1.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3pbv]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3pbv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Metth Metth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PBV FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UP6:6-AZA+URIDINE+5-MONOPHOSPHATE'>UP6</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UP6:6-AZA+URIDINE+5-MONOPHOSPHATE'>UP6</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3g18|3g18]], [[3lhw|3lhw]], [[3ltp|3ltp]], [[3lts|3lts]], [[3lty|3lty]], [[3lv5|3lv5]], [[3lv6|3lv6]], [[3nq6|3nq6]], [[3nq7|3nq7]], [[3nqa|3nqa]], [[3nqc|3nqc]], [[3nqd|3nqd]], [[3nqe|3nqe]], [[3nqf|3nqf]], [[3nqg|3nqg]], [[3nqm|3nqm]], [[3p5y|3p5y]], [[3p5z|3p5z]], [[3p60|3p60]], [[3p61|3p61]], [[3pbu|3pbu]], [[3pbw|3pbw]], [[3pby|3pby]], [[3pc0|3pc0]], [[3sy5|3sy5]], [[3siz|3siz]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3g18|3g18]], [[3lhw|3lhw]], [[3ltp|3ltp]], [[3lts|3lts]], [[3lty|3lty]], [[3lv5|3lv5]], [[3lv6|3lv6]], [[3nq6|3nq6]], [[3nq7|3nq7]], [[3nqa|3nqa]], [[3nqc|3nqc]], [[3nqd|3nqd]], [[3nqe|3nqe]], [[3nqf|3nqf]], [[3nqg|3nqg]], [[3nqm|3nqm]], [[3p5y|3p5y]], [[3p5z|3p5z]], [[3p60|3p60]], [[3p61|3p61]], [[3pbu|3pbu]], [[3pbw|3pbw]], [[3pby|3pby]], [[3pc0|3pc0]], [[3sy5|3sy5]], [[3siz|3siz]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 METTH])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pbv OCA], [https://pdbe.org/3pbv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pbv RCSB], [https://www.ebi.ac.uk/pdbsum/3pbv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pbv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 3pbv" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3pbv" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Uridine 5'-monophosphate synthase 3D structures|Uridine 5'-monophosphate synthase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Metth]] | [[Category: Metth]] | ||
[[Category: Orotidine-5'-phosphate decarboxylase]] | [[Category: Orotidine-5'-phosphate decarboxylase]] |